Difference between revisions of "20.109(S17):Module 1"
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==References== | ==References== | ||
| − | [[Media:Sp17 M1 reference NatProt.pdf| A method for the covalent capture and screening of diverse small molecules in a microarray format.]] ''Nature Protocols.'' 1:2344-2352. | + | *[[Media:Sp17 M1 reference NatProt.pdf| A method for the covalent capture and screening of diverse small molecules in a microarray format.]] ''Nature Protocols.'' 1:2344-2352. |
| − | [[Media:Sp17 M1 reference ChemBiol.pdf| Recent discoveries and applications involving small-molecule microarrays.]] ''Chemical Biology.'' 18:21-28. | + | *[[Media:Sp17 M1 reference ChemBiol.pdf| Recent discoveries and applications involving small-molecule microarrays.]] ''Chemical Biology.'' 18:21-28. |
==Notes for teaching faculty== | ==Notes for teaching faculty== | ||
[[20.109(S17): TA notes for M1| S17 notes for M1]] | [[20.109(S17): TA notes for M1| S17 notes for M1]] | ||
[[20.109(S17): TA notes for orientation| S17 notes for orientation day]] | [[20.109(S17): TA notes for orientation| S17 notes for orientation day]] | ||
Revision as of 22:49, 30 January 2017
Contents
Module 1
Lecturer: Angela Koehler
Instructors: Noreen Lyell, Leslie McClain and Maxine Jonas
TA: Rob Wilson
Lab manager: Hsinhwa Lee
Overview
Lab links: day by day
M1D1: In silico cloning and induce protein expression
M1D2: Purify induced protein
M1D3: Evaluate purity and concentration of protein
M1D4: Screen ligand library for FKBP12 binders
M1D5: Scan slides to identify FKBP12 binders
M1D6: Complete data analysis
M1D7: Identify chemical structures common among FKBP12 binders
Data
See all M1 student data on the Discussion page.
Assignments
Data summary
Mini-presentation
References
- A method for the covalent capture and screening of diverse small molecules in a microarray format. Nature Protocols. 1:2344-2352.
- Recent discoveries and applications involving small-molecule microarrays. Chemical Biology. 18:21-28.
