Difference between revisions of "20.109(S09): siRNA design (Day1)"
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==Introduction== | ==Introduction== | ||
− | In the previous experimental module, your work focused on proteins, and to implement protein modifications, you manipulated DNA. In this experimental module, RNA gets the spotlight. While DNA | + | In the previous experimental module, your work focused on proteins, and to implement protein modifications, you manipulated DNA. In this experimental module, RNA gets the spotlight. While DNA almost exclusively functions to encode the genetic information of a cell, RNA is remarkably versatile. The scientific literature on RNA includes reports of enzymatically active RNAs called ribozymes (indeed, our DNA/RNA/protein world is thought to have evolved from an RNA-based one), and RNAs that directly regulate transcription and translation. RNA has long been used as a readout for gene expression but has only recently been appreciated as a tool for manipulating gene expression. |
− | The term | + | The term |